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KMID : 0358320090500030237
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Korean Journal of Urology
2009 Volume.50 No. 3 p.237 ~ p.240
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Prostate Cancer Detection Rate of Rebiopsy in Patients with an Initial Diagnosis of Atypical Small Acinar Proliferation of the Prostate
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Oh Jung-Woo
Kim Yun-Beom
Yang Seung-Ok
Lee Jeong-Ki
Kim Yoon-Jung
Jung Tae-Young
Shim Hong-Bang
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Abstract
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Purpose: Atypical small acinar proliferation (ASAP) denotes the presence of suspicious glands with insufficient cytological architecture for a definitive prostate cancer diagnosis. We evaluated the subsequent prostate cancer detection rate of rebiopsy in patients with an initial diagnosis of ASAP.
Materials and Methods: Between January 2003 and December 2006, 1,416 men with suspected prostate cancer underwent a transrectal ultrasound- guided prostate biopsy, and 214 (15.1%) were diagnosed as having ASAP. Ninety-five of the 215 patients underwent at least one more biopsy. We evaluated the cancer detection rates after rebiopsy.
Results: In men with ASAP, 36 patients (37.9%) had prostate cancer. The cancer detection rates of the 1st, 2nd, and 3rd rebiopsies were 30.5%, 23.8%, and 40%, respectively. Mean patient age and prostate-specific antigen did not differ significantly between the prostate cancer and noncancer groups after rebiopsy. Prostate volume, however, was significantly smaller in the cancer group (p＜0.05).
Conclusions: Our results showed a detection rate for prostate cancer of 37.9% after an initial diagnosis of ASAP, which indicates that an initial diagnosis of ASAP mandates rebiopsy.
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KEYWORD
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Atypical small, acinar, proliferation, Biopsy, Prostatic, neoplasms
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